Susan Band Horwitz ’58 will receive the American Association for Cancer Research Award for Lifetime Achievement in Cancer Research on April 3, 2011. The award is given to an individual who has made significant fundamental contributions to cancer research, either through a scientific discovery or a body of work. Horwitz discovered the mechanism of action of the chemotherapeutic drug paclitaxel, which promoted the drug for therapy for solid tumors including ovarian, breast, and lung carcinomas. She also contributed to the understanding of how microtubules function in normal and malignant cells and why stabilization of microtubules is a promising target for drug discovery.
Horwitz is a member of the American Academy of Arts, the National Academy of Sciences, and the Institute of Medicine. She is a fellow of the National Foundation for Cancer Research and the American Society of Pharmacognosy. She has received numerous other awards, including the ASPET Award for Experimental Therapeutics, the American Cancer Society’s Medal of Honor, and the Warren Alpert Foundation Award from Harvard Medical School. She also received a Doctor Honoris Causa, Universite de la Mediterranee, Marseilles, France.